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Although one should never pin too much hope on drug trials to treat Alzheimers, as so much earlier work has failed, there is widespread disappointment at the findings

Thyroid hormone production, apoptosis, and immunological dysfunction have all been associated with dysregulation of miRNAs

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These properties were attributed to antioxidant, anti-inflammatory, and anti-apoptotic mechanisms, including suppression of NF-B and downstream of the inflammatory cytokines TNF and IL-6